Publications 2013 - 2014
2014
Ibrahim MIM, Awaisu A, Atwa H, Radoui A, Kheir N, Maarup N. How do community pharmacists in Qatar respond to patients presenting with symptoms of acute respiratory tract infections? Journal of Pharmacy Practice and Research 2014;44:62-3.
Mohamed IA, Mraiche F. Targeting osteopontin, the silent partner of NA+ /H+ exchanger isoform 1 in cardiac remodeling. J Cell Physiol. 2015. DOI 10.1002/jcp.24958 (link)
Selmi S, Daghash G, Mathis S, Nahas K, Wilbur K. A program for obese youth at-risk for diabetes in Qatar. Avicenna 2014;1:2. DOI 10.5339/avi.2015.2 (link)
Cartwright AL, Wilby KJ. A critical evidence-based summary of the use of beta-blockers in stable coronary artery disease. Avicenna 2014:4. (link)
Zolezzi M, Bye L, Harrison J, Tsuyuki R, Shaw J. Provision of health /disease screening and medication monitoring/management in New Zealand community pharmacies. Journal of Pharmacy Practice and Research 2014;44, 188-194. (link)
Anggriani Y, Ibrahim MIM, Suryawati S, Shafie AA. The impact of Indonesian generic medicine pricing policy on medicine prices. Journal of Generic Medicines 2014. DOI 10.1177/1741134314553605 (link)
Al-Salimy N, Awaisu A. Methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa for anemia in non-dialysis-dependent CKD: a systematic review. Int J Clin Pharm 2014;36(6):1115-25. DOI 10.1007/s11096-014-0023-x (link)
Awaisu A, Bakdach D, Elajez RH, Zaidan M. Hospital pharmacists' self-evaluation of their competence and confidence in conducting pharmacy practice research. SPJ 2014; DOI 10.1016/j.jsps.2014.10.002 (link)
Babiker AH, Carson L, Awaisu A. Medication use review in Qatar: Are community pharmacists prepared for the extended professional role? Int J Clin Pharm 2014;36(6):1241-50. DOI 10.1007/s11096-014-0025-8 (link)
Khanizadeh H, Nikkhah K, Ibrahim MIM. The characteristics of multiple sclerosis in Iran. Value in Health 2014;17:A392–A393. (link)
Khanizadeh H, Ibrahim MIM, Nikkhah K. Pharmacoeconomic aspects of multiple sclerosis treatments in Iran. Value in Health 2014;17:A395–A396. (link)
Ibrahim MIM, A. Awaisu, S. Berzou, R. Abu Samaha, S. Elshami, M. Elhafiz, I. Babiker. Management of type 2 diabetes mellitus among patients attending a primary health care setting in Qatar: a study on medication use pattern and clinical outcomes. Value in Health 2014;17:A335. (link)
Awaisu A, Ibrahim MIM, Kheir N, ElHajj M. Promoting quality use of generic medicines: knowledge, attitudes and practices of community pharmacists in a middle eastern country. Value in Health 2014;17:A412. (link)
Awaisu A, Kheir N, Ibrahim MIM, Al-Taweel HM, Elmubark AE. Implementation of an ambulatory pharmacist-managed anticoagulation clinic in qatar: development of a new service and a pilot on patients' satisfaction and quality of life. Value in Health 2014;17:A515. (link)
Farghali AA, Al-Khawaja R, Madi L, Elbardissy A, Hamdy HM, Wilby KJ. Rigorous method to assess quality and generalizability of clinical practice guidelines. Canadian Journal of Hospital Pharmacy 2014;67(5):397-398. (link)
Bains S, Kitutu FE, Rahhal A, Samaha RA, Wilby KJ, Rowe H. Comparison of pharmacist knowledge, perceptions and training opportunities regarding maternal-feral medicine in Canada, Qatar, and Uganda. Canadian Pharmacists Journal 2014;147(6):345-351. (link)
Szymanski PT, Ahmed SA, Radwan MM, Khalifa SI, Fahmy H. Evaluation of anti-melanoma activities of (1S,2E,4R,6E,8R,11S,12R)-8,12-epoxy-2,6-cembradiene-4,11-diol, (1S,2E,4R,6E,8S,11R,12S)-8,11-epoxy-4,12-epoxy-2,6-cembradiene and (1S,4R,13S)-cembra-2E,7E,11E-trien-4,13-diol from the Red Sea soft coral sarcophyton glaucum. Nat Prod Commun. 2014;9(8):1143-6. (link)
Alrasheedy AA, Hassali MA, Stewart K, Kong DCM, Aljadhey H, Ibrahim MIM, Al-Tamimi SK. Patient knowledge, perceptions, and acceptance of generic medicines: a comprehensive review of the current literature. Patient Intelligence 2014;6:1-29. (link)
Kiang TK, Wilby, KJ, Ensom MHH. Clinical pharmacokinetic and pharmacodynamic drug interactions associated with antimalarials. New York: Springer, 2014. ISBN 978-3-319-10526-0. (link)
Frank R, WIlby KJ, Mamdani MM. Cross-national comparison of levothyroxine utilization in four developed countries. J Health Specialties 2014;2(4):152-155.
Elkalmi RM, Hassali MA, Ibrahim MIM, Jamshed SQ, Al-lela OQ. Community pharmacists' attitudes, perceptions, and barriers toward adverse drug reaction reporting in Malaysia: a quantitative insight. Journal of Patient Safety 2014;10:81-87. (link)
Mohamed Awad M, Akmal SA, Ibrahim MIM. Systematic review of factors affecting pharmaceutical expenditures. Health Policy 2014;116:137–146. (link)
Wilby KJ, Ensom MHH, Marra F. Review of evidence for measuring drug concentrations of first-line anti-tubercular agents in adults. Clinical Pharmacokinetics 2014;53:873-890. (link)
Alfadl AA, Ibrahim MIM, Hassali MAA. How ethics influence intentions to buy counterfeit drugs: perceptions of policymakers, community pharmacists and consumers in Sudan. Journal of Pharmaceutical Health Services Research 2014;5:181–186. (link)
Wilby KJ, Mohamad AA, AlYafei SA, Evaluation of clinical pharmacy services offered for palliative patients in Qatar. Journal of Pain and Palliative Care Pharmacotherapy 2014;28(3):212-5. DOI 10.3109/15360288.2014.938884
Haji H, Wilby KJ, Mamdani M. A comparison of warfarin utilisation in North America and Ireland. Journal of Health Specialties 2014;2(3):105-8. DOI 10.4103/1658-600X.137883
Kheir N, Awaisu A, Sharfi A, Kida M, Adam A. Drug-related problems identified by pharmacists conducting medication use reviews at a primary health center in Qatar. IJCP 2004. DOI 10.1007/s11096-014-9962-5
Wilby KJ, Al-Abdi T, Hassan A, Brown MA, Paravattil B, Khalifa SI. Attitudes of pharmacy and nutrition students towards team-based care after first exposure to interprofessional education in Qatar. J Interprof Care 2014. DOI 10.3109/13561820.2014.933949
Black EK, Wilby KJ, Jewesson PJ. International exposure to pharmacy leadership, education and practice: the early Qatar experience. Pharmacy Education 2014;14(1):69-74. (link)
Staudenmire LG, DeRemer CE, Elewa HF. Telephone versus office-based management of warfarin: impact on international normalized ratios and outcomes. 2014. DOI 10.1007/s12185-014-1619-6 (link)
Elewa HF, DeRemer CE, Keller JK, Gujral J. Patients satisfaction with warfarin and willingness to switch to dabigatran: a patient survey. J Thromb Thrombolysis, 2014;38(1):115-20. DOI 10.1007/s11239-013-0976-y (link)
Pawluk S, Black E, El-Awaisi A. Strategies for improving antibiotic use in Qatar: a survey of pharmacists' perceptions and experiences. Int J Pharm Pract. 2014. DOI 10.1111/ijpp.12108 (link)
Black E, Cartwright A, Bakharaiba S, Al-Mekaty E, Alsahan D. A qualitative study of pharmacists' perceptions of, and recommendations for antibiotic use in Qatar. Int J Clin Pharm. 2014. (link)
Imam A, Al-Salloom AA, Ibrahim MIM, Elsanosi BH, Al-Wabel AH. Student presentation: a conceptual model. Education in Medicine Journal 2014;6:e57-61. (link)
Alali F, Amrine S, El-Elimat T, Alkofahi A, Tawaha K, Gharaibah M, Swanson S, Falkinham III J, Cabeza M, Sánchez A, Figueroa M, Oberlies N. Bioactive withanolides from withania obtusifolia. Phytochemistry Letters 2014;9:96-101. (link)
Wilbur K, Al Tawengi K, Remoden E. Diabetes patient management by pharmacists during Ramadan. BMC Health Services Research 2014;14:117. (link)
Szymanski PT, Ahmed SA. Ahmed, Radwan MM, Khalifa SI, Fahmy H. Evaluation of the anti-melanoma activities of sarcophine, (+)-7α,8β dihydroxydeepoxysarcophine and sarcophytolide from the red sea soft coral sarcophyton glaucum. Nat Prod Commun. 2014;9:151-54.
Ibrahim MIM, Abdelrahim HE, Ab Rahman AF. Cost evaluation of therapeutic drug monitoring of gentamicin at a teaching hospital in Malaysia. Pharmacy Practice 2014;12:372-77. (link)
Anwar-Mohamed A, Elshenawy O, Soshilov A, Denison M, ChrisLe X, Klotz L, El-Kadi A. Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P4501A1 and NAD(P)H:quinone oxidoreductase through AhR-and Nrf2-dependent mechanisms. Free Radical Biology and Medicine 2014; (67) 171-187. (link)
Amaraa I, Elshenawy O, Abdelrady M, El-Kadi A. Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P4501A1 and NAD(P)H:quinone oxidoreductase through AhR-and Nrf2-dependent mechanisms. Toxicology Letters 2014; (226) 53-62.
Awaisu A, Kheir N, Mohamed Ibrahim MI, El-Hajj M, Hazi H, Khudair N, Barazi R. Knowledge, attitudes, and practices of community pharmacists on generic medicines in Qatar. Int J Clin Pharm. 2014. DOI 10.1007/s11096-013-9909-2 (link)
El Hajj M, Hammad A, Afifi HM Pharmacy students’ attitudes toward pharmaceutical care in Qatar. Therapeutics and Clinical Risk Management 2014:10 121-129. (link)
Ahmed SA, Mesbah MK, Youssef DT, Khalifa SI. Microbial production of 1a-hydroxyvitamin D3 from vitamin D3. Nat Prod Res 2014. DOI 10.1080/14786419.2013.872104 (link)
Kiang TL, Wilby KJ, Ensom MHH. Clinical pharmacokinetic drug interactions associated with artemisinin derivatives and HIV-antivirals. Clinical Pharmacokinetics 2014;53:141-153. DOI 10.1007/s40262-013-0110-5
Kheir N, Atwa HG, E Abu-Yousef S. Pharmacists’ knowledge and attitudes about natural health products: a mixed-methods study. Drug, Healthcare and Patient Safety 2014:6 7-14. (link)
2013
Anaam MS, Ibrahim MIM, Al Serouri AW, Aldobhani A. Factors affecting patients' compliance to anti-tuberculosis treatment in Yemen. Journal of Pharmaceutical Health Services Research 2013;4:115-122. (link)
Gujral J, Elewa HF, (2013). Clinical medicine - a practical manual for emergency medicine and tropical disease. In BB. Rewari (Ed), Recent advances in anticoagulation therapy (pp.150-156). New Delhi, India: Jaypee Brothers Medical Publishers (link)
NEJM Supplement to: Kimmel SE, French B, Kasner SE, et al. A pharmacogenetic versus a clinical algorithm for warfarin dosing. N Engl J Med 2013. DOI 10.1056/NEJMoa1310669 (link)
Alamin Hassan MAA, Ibrahim MIM, Mohamed Azmi AH. Do professional practices among Malaysian private healthcare providers differ? a comparative study using simulated patients. Journal of Clinical and Diagnostic Research. 2013;7:2912-2916. (link)
Hussain A, Ibrahim MIM, Malik M. Assessment of disease management of insomnia at community pharmacies through simulated visits in Pakistan. Pharmacy Practice 2013 Oct-Dec;11(4):179-184. (link)
Dawood OT, Mohamed Izham MI, Abdullah AC. Children’s knowledge and beliefs about medicines. Journal of Child Health Care 2013. DOI 10.1177/1367493513496911 (link)
Jacob SA, Ibrahim MIM, Mohammed F. Polypharmacy in the management of patients with schizophrenia on risperidone in a tertiary-care hospital in Malaysia. Ment Health Fam Med. 2013;10:37-43. (link)
Fatokun O, Ibrahim MIM, Mohamed Azmi AH. Time to entry of generic medicines in Malaysia: implications for pharmaceutical cost containment. Journal of Pharmaceutical Health Services Research 2013;4:203-10. (link)
Alrasheedy AA, Hassali MA, Aljadhey H, Ibrahim MIM, Al-Tamimi SK. Is there a need for a formulary of clinically interchangeable medicines to guide generic substitution in Saudi Arabia? J Young Pharm. 2013;5(2):73-75. (link)
Wilbur K. Pharmacovigilance in Qatar: a survey of pharmacists. Eastern Mediterranean Health Journal 2013; 19:930-5. (link)
Alamin Hassan MAA, Ibrahim MIM, Mohamed Azmi AH. Dispensing practices of general practitioners and community pharmacists in Malaysia - a pilot study. Journal of Pharmacy Practice and Research 2013;43:187-89. (link)
Alshakka MA, Ibrahim MIM, Hassali MAA. Do health professionals have positive perception towards consumer reporting of adverse drug reactions? Journal of Clinical and Diagnostic Research 2013;7:2181-85. (link)
Black E, Wilby K, Perepelkin J. A survey of HIV knowledge and attitudes of pharmacy students in Canada and Qatar. Saudi J Health Sci 2013;2(3):146-50. DOI 10.4103/2278-0521.127038 (link)
Eyler R, Vilay A, Nader A, Heung M, Pleva M, Sowinski K, DePestel D, Sörgel F, Kinzig M, Mueller B. Pharmacokinetics of ertapenem in critically ill patients receiving continuous venovenous hemodialysis (CVVHD) or hemodiafiltration (CVVHDF). Antimicrob. Agents Chemother. DOI 10.1128/AAC.02090-12 (link)
Bains S, Rowe H, Wilby KJ. Pharmacists and maternal-fetal medicine: development of a tool to characterize knowledge and current practice. Journal of Maternal Fetal & Neonatal Medicine 2013. DOI 10.3109/14767058.2013.825602 (link)
Turner SJ, Senol E, Kara A, Al-Badriyeh D, Dinleyici EC, Kong DC. Pharmacoeconomic evaluation of voriconazole vs. liposomal amphotericin B in empiric treatment of invasive fungal infections in Turkey. BMC Infect Dis. 2013;13:560. DOI 10.1186/1471-2334-13-560 (link)
Turner SJ, Senol E, Kara A, Al-Badriyeh D, Kong DC, Dinleyici EC. Pharmacoeconomic evaluation of caspofungin versus liposomal amphotericin B in empirical treatment of invasive fungal infections in Turkey. Int J Antimicrob Agents. 2013;42(3):276-80. DOI 10.1016/j.ijantimicag (link)
Hammuda A, Hayder S, Elazzazy S, Black E. Point prevalence survey of antimicrobial utilization in oncology patients. J Infect Dev Ctries 2013;7(12):990-3. (link)
Alfadl AA, Ibrahim MIM, Hassali MAA. Scale development on consumer behavior toward counterfeit drugs in a developing country: a quantitative study exploiting the tools of an evolving paradigm. BMC Public Health 2013;13:829. DOI 10.1186/1471-2458-13-829 (link)
Kheir N, Awaisu A, Radoui A, El Badawi A, Jean L, Dowse R. Development and evaluation of pictograms on medication labels for patients with limited literacy skills in a culturally diverse multiethnic population. Research in Social and Administrative Pharmacy 2013. DOI 10.1016/j.sapharm.2013.11.003 (link)
Nader A, Foster D. Suitability of digoxin as a p-glycoprotein probe: implications of other transporters on sensitivity and specificity. Journal of Clinical Pharmacology 2013. DOI 10.1002/jcph.200
Broncz I, Kalo Z, Ibrahim MIM, Greenberg D. Editorial. Further steps in the development of pharmacoeconomics, outcomes research, and health technology assessment in central and Eastern Europe, Western Asia, and Africa. Value in Health Regional 2013;2:169-170. (link)
Al-Hamdi AY, Ibrahim MIM, Ahmad Hassali MA. The role of healthcare professionals in establishing unhealthy pharmaceutical promotion activities in Yemen. Journal of Medical Marketing 2013;13:142-150. (link)
Abubakr AA, Mohamed Azmi AH, Mohamed Izham M.I. Counterfeit drug demand: perceptions of policy makers and community pharmacists in Sudan. Research in Social and Administrative Pharmacy 2013;9:302-10. (link)
Hussain A, Ibrahim MIM, Malik M. Impact of educational intervention on knowledge of dispensers working at community pharmacies in Pakistan. Pharmacy Practice 2013;11:144-148. (link)
Wilby K, Al-Siyabi K. Evidence-based healthcare practice in Qatar: a need to move forward. Avicenna 2013:7. (link)
Wilby KJ, Herrmann N, Mamdani MM. Cross-national comparison of antidepressant utilization in North America and Europe. Journal of Clinical Psychopharmacology 2013;33(4):585-7. (link)
Helal, MA, Khalifa SI, Ahmed SA. Differential binding of latrunculins to G-actin: a molecular dynamics study. J Chem Inf Model 2013. DOI 10.1021/ci400317j (link)
Mamdani MM, Wilby KJ. International variation in drug utilization: antidepressant utilization in North America, Greece, and Ireland. Journal of Health Specialties 2013;1:78-83. (link)
Wilby KJ, Gilchrist SE, Ensom MHH. A review of the pharmacokinetic implications of schistosomiasis. Clinical Pharmacokinetics 2013;52(8):647-56. (link)
Kiang T, Wilby KJ, Ensom MHH. Telaprevir: Clinical pharmacokinetics, pharmacodynamics, and drug-drug interactions. Clinical Pharmacokinetics 2013;27:487-510. (link)
Elgaily DE, Sahal AO, Orabi BA, Ibrahim DA, Wilby KJ. Should clinical practitioners, as part of institutional or accreditation standards, be required to document their rationale when choosing to not adhere to widely accepted clinical practice guidelines (con). Canadian Journal of Hospital Pharmacy 2013;66(4):253-5.
El Kassem W, Abdulrahman A, Raghab A, Wilbur KL. Should clinical practitioners, as part of institutional or accreditation standards, be required to document their rationale when choosing to not adhere to widely accepted clinical practice guidelines (pro). Canadian Journal of Hospital Pharmacy 2013;66(4):253-5.
Wilbur K, Hazi H, El-Bedawi A. Drug-related hospital visits and admissions associated with laboratory or physiologic abnormalities - a systematic-review. PLOS ONE 2013;8(6):e66803. DOI 10.1371/journal.pone.0066803 (link)
Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC, Wang J, Liu N, Tatonetti N, Bourgeois S, Takahashi H, Bradford Y, Burkley BM, Desnick RJ, Halperin JL, Khalifa SI, Langaee TY, Lubitz SA, Nutescu EA, Oetjens M, Shahin MH, Patel SR, Sagreiya H, Tector M, Weck KE, Rieder MJ, Scott SA, Wu AHB, Burmester JK, Wadelius M, Deloukas P, Wagner MJ, Mushiroda T, Kubo M, Roden DM, Cox NJ, Altman RB, Klein TE, Nakamura Y, Johnson JA. Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. The Lancet 2013. (link)
Kheir N, Al Saad D, Al Naimi S. Pharmaceutical care in the Arabic-speaking Middle East: literature review and country informant feedback. Avicenna 2013:2. (link)
Kheir N. An Arab pharmacy spring: taking matters in their own hands. Int J Clin Pharm 2013; DOI 10.1007/s11096-013-9808-6
Khanal S, Ibrahim MIM, Shankar PR, Palaian S, Mishra P. Evaluation of academic detailing programme on childhood diarrhoea management by primary healthcare providers in Banke district of Nepal. J Health Popul Nutr 2013;31:231-242.
Black E, Campbell SG, Magee K, Zed P. Propofol for procedural sedation in the emergency department: a qualitative systematic review. Ann Pharmacother 2013;47:856-68. (link)
Fatokun O, Ibrahim MIM, Hassali MA. Factors determining the post-patent entry of generic medicines in Malaysia: a survey of the Malaysian generic pharmaceutical industry. Journal of Generic Medicines 2013;10:22–33.
Bhuvan KC, ALrasheedy AA, Ibrahim MIM. A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain. Saudi Pharmaceutical Journal 2013;21:323–325.
Wilbur K. Using daily newspapers to develop professional literacy - a descriptive study. Advances in Medical Education and Practice 2013;4:95–99.
Awaisu A, Hagi A, Ashour MA, Kheir N. Pictorial health warnings on cigarette packages in Qatar: preimplementation awareness and perceptions of ever-smokers versus never-smokers. Nicotine Tob Res 2013. DOI 10.1093/ntr/ntt059 (link)
Wilby KJ, Lacey J. Pharmacist-led medication-related needs assessment in rural Ghana. SpringerPlus 2013;2:163. DOI 10.1186/2193-1801-1-163 (link)
Ibrahim MIM, Al-Sulaiti FK, Elshami SS. Do community pharmacists in Qatar practice rationally for a minor ailment? Journal of Pharmacy Practice and Research 2013;43:79.
Al-Badriyeh D et al. International society of pharmacoeconomics and outcomes research (ISPOR) book of terms - Arabic version. Translator/Reviewer. New Jersey: ISPOR; 2013. (link)
Bhuvan KC, Alrasheedy AA, Ibrahim MIM. Do community pharmacists in Nepal have a role in adverse drug reaction reporting systems? Australasian Medical Journal 2013;6:100-103.
Cartwright AL, Wilby KJ, Corrigan S, Ensom MHH. Pharmacogenetics of risperidone: a systematic review of the clinical effects of CYP2D6 polymorphisms. Annals of Pharmacotherapy 2013;47:350-60. (link)
Wilby KJ. Structured practical experience for Canadian student pharmacists in Ghana. International Journal of Pharmacy Practice 2013;21:135-6.
Fatokun O, Ibrahim MIM, Mohamed Azmi AH. Generic industry’s perceptions of generic medicines policies and practices in Malaysia. Journal of Pharmacy Research 2013;7:80-84.
Szymanski PT, Ahmed SA, Khalifa SI, Tokuda H, Ichiishie E, Iida A, Suzuki N, Fahmy H. Chemopreventive effect of sarcophine-diol on NOR-1-induced TPA-promoted skin carcinogenesis in female HOS:HR-1 mice. Nat Prod Commun 2013;8:153-54.
Wilbur K. Pharmacovigilance in the Middle East. Drug Safety 2013;36:25-30. (link)
Mousnad MA, Shafie AA, Ibrahim MIM. Determination of the main factors contributing to increases in medicine expenditures for the National Health Insurance Fund in Sudan. Journal of Pharmaceutical Health Services Research 2013. DOI 10.1111/jphs.12017
Abou El-Ezz RF, Ahmed SA, Radwan MM, Ayoub NA, Afifi MS, Ross SA, Szymanski PT, Fahmy H, Khalifa SI. Bioactive cembranoids from the Red Sea soft coral Sarcophyton glaucum. Tetrahedron Letters 2013;54:989–992.
Heng SC, Slavin MA, Al-Badriyeh D, Kirsa S, Seymour JF, Grigg A, Thursky K, Bajel A, Nation RL, Kong DCM. Pharmacoeconomic evaluation of fluconazole, posaconazole and voriconazole for antifungal prophylaxis in patients with acute myeloid leukaemia undergoing first consolidation chemotherapy. J. Antimicrob. Chemother. 2013. DOI 10.1093/jac/dkt068
Pawluk S, Wilby KJ, Ensom MHH. Pharmacokinetic profile of artemisinin derivatives and companion drugs used in artemisinin-based combination therapies for the treatment of Plasmodium falciparum malaria in children. Clinical Pharmacokinetics 2013;52:153-67. (link)
Metwally K, Khalil A, Sallam A, Pratsinis H, Kletsas D, El Sayed K. Structure–activity relationship investigation of methoxy substitution on anticancer pyrimido[4,5-c]quinolin-1(2H)-ones. Med Chem Res 2013. DOI 10.1007/s00044-012-0428-9